There is strong evidence for brain-related pathologies in COVID-19, some of which could be a consequence of viral neurotropism. The vast majority of brain imaging studies so far have focused on qualitative, gross pathology of moderate to severe cases, often carried out on hospitalised patients. It remains unknown however whether the impact of COVID-19 can be detected in milder cases, in a quantitative and automated manner, and whether this can reveal a possible mechanism for the spread of the disease. UK Biobank scanned over 40,000 participants before the start of the COVID-19 pandemic, making it possible to invite back in 2021 hundreds of previously-imaged participants for a second imaging visit. Here, we studied the effects of the disease in the brain using multimodal data from 782 participants from the UK Biobank COVID-19 re-imaging study, with 394 participants having tested positive for SARS-CoV-2 infection between their two scans. We used structural and functional brain scans from before and after infection, to compare longitudinal brain changes between these 394 COVID-19 patients and 388 controls who were matched for age, sex, ethnicity and interval between scans. We identified significant effects of COVID-19 in the brain with a loss of grey matter in the left parahippocampal gyrus, the left lateral orbitofrontal cortex and the left insula. When looking over the entire cortical surface, these results extended to the anterior cingulate cortex, supramarginal gyrus and temporal pole. We further compared COVID-19 patients who had been hospitalised (n=15) with those who had not (n=379), and while results were not significant, we found comparatively similar findings to the COVID-19 vs control group comparison, with, in addition, a greater loss of grey matter in the cingulate cortex, central nucleus of the amygdala and hippocampal cornu ammonis (all |Z|>3). Our findings thus consistently relate to loss of grey matter in limbic cortical areas directly linked to the primary olfactory and gustatory system. Unlike in post hoc disease studies, the availability of pre-infection imaging data helps avoid the danger of pre-existing risk factors or clinical conditions being mis-interpreted as disease effects. Since a possible entry point of the virus to the central nervous system might be via the olfactory mucosa and the olfactory bulb, these brain imaging results might be the in vivo hallmark of the spread of the disease (or the virus itself) via olfactory and gustatory pathways.
https://www.medrxiv.org/content/10.1101/2021.06.11.21258690v1.full
- For PayPal digital payments with its PayPal Checkout, Pay with Venmo, PayPal Credit, Pay in 4, PayPal Pay with Rewards, and Checkout with crypto, the new rate for online transactions will be 3.49 percent plus $0.491 per transaction.
- For in person payments with PayPal and Venmo QR code transactions over $10, the rate will be 1.90 percent plus 10 cents, and for transactions $10 and less, the rate will be 2.40 percent plus 5 cents. For certain in-person debit and credit transactions the rate will be 2.29 percent plus 9 cents.
- The rate for online credit and debit card transactions will be 2.59 percent plus $0.491 per transaction without its chargeback protection, and with chargeback protection the rate will be 2.99 percent plus 49 cents.
- The fee for charity transactions will be 1.99 percent plus 49 cents.
- For US merchants who have custom, non-standard pricing, rates will remain unchanged
Rumors are that in 2022 we can see 5% .
For the second quarter of fiscal year 2021, which ended for Adobe on June 4, the company generated revenue of $ 3.84 billion, which corresponds to an increase of 23% over the same period last year. Adjusted earnings of $ 3.03 per share. The company's results were better than analysts' expectations, who had forecast $ 3.73 billion in quarterly profit on earnings per share of $ 2.82.
Sales in the Digital Media segment, which includes creative divisions and cloud-based document editing services, jumped 25% to $ 2.79 billion. Sales in the Digital Experience segment, which includes marketing software, grew 21% to $ 938 million Amid the announcement of financial results, the company's shares rose by almost 2.5% and traded at $ 551.36 per share.
In the third quarter of this year, Adobe expects to receive revenue of $ 3.88 billion, which is slightly higher than analysts' forecasts, which on average expect $ 3.83 billion in revenue. The company also expects to receive adjusted earnings of $ 3 per share, while analysts forecast earnings of $ 2.90 per share.
At the same time biggest questions discussed inside US office is... diversity and prevention of white supremacism. One of developers told me in May that at least on two meetings such questions took more than 60% of total time, 20% of remaining time had been spend on discussing fuckups of new "diversified" developers.
And still any people who try to make any optimization or fix old bugs get very dark future ahead of them - all their marks suddenly become lower and their income and bonuses also plummet.
New cameras
Used cameras
Roskomnadzor began to restrict access to violating VPN services, which are used to bypass blocking of any good content and protect their privacy on the Internet. This was reported on Thursday with reference to the release of the service.
On Thursday, Roskomnadzor began blocking VyprVPN and Opera VPN "in accordance with the regulations for responding to threats to circumvent restrictions on access to child pornography, suicidal, pro-drug and other prohibited content."
The service explained to the publication that these services are classified as threats in accordance with a government decree.
"The restrictions will not affect Russian companies using VPN services in continuous technological processes," added Roskomnadzor, adding that more than 200 such processes in 130 Russian companies are included in the "white lists". Enterprises were informed about the possibility of inclusion in the lists on May 14, 2021, the lists can be supplemented after relevant requests
Note how it is always "child pornography, suicidal, pro-drug content"? As if had been possible they will do anything to promote and make all of this things very common (as they love all of them!), but they are so nice tiny size things that allow to dumb down masses.
Tech company Canon has come up with a downright dystopic way to tackle the problem of workplace morale: it’s installed cameras with AI-enabled “smile recognition” technology in the offices of its Chinese subsidiary Canon Information Technology. The cameras only let smiling workers enter rooms or book meetings, ensuring that every employee is definitely, 100 percent happy all the time.
https://www.ft.com/content/b74b6ad6-3b8d-4cd8-9dd6-3b49754aa1c7
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